High-level acetaldehyde production in Lactococcus lactis by metabolic engineering.
نویسندگان
چکیده
Efficient conversion of glucose to acetaldehyde is achieved by nisin-controlled overexpression of Zymomonas mobilis pyruvate decarboxylase (pdc) and Lactococcus lactis NADH oxidase (nox) in L. lactis. In resting cells, almost 50% of the glucose consumed could be redirected towards acetaldehyde by combined overexpression of pdc and nox under anaerobic conditions.
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ورودعنوان ژورنال:
- Applied and environmental microbiology
دوره 71 2 شماره
صفحات -
تاریخ انتشار 2005